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Topoisomerase II inhibitor 14
CAS No. 305343-00-4
Topoisomerase II inhibitor 14 ( —— )
产品货号. M37019 CAS No. 305343-00-4
Topoisomerase II inhibitor 14 (compound 2f) 是拓扑异构酶 II 的有效抑制剂，具有抗癌活性。Topoisomerase II inhibitor 14 诱导细胞凋亡，并将细胞周期阻滞在 S 期。Topoisomerase II inhibitor 14 具有抗氧化作用并降低 GSH、MDA 和 NO 的水平。
纯度: >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| 规格 | 价格/人民币 | 库存 | 数量 |
| 2MG | ￥2041 | 有现货 |
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| 5MG | ￥2850 | 有现货 |
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| 10MG | ￥4142 | 有现货 |
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| 25MG | ￥6397 | 有现货 |
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| 50MG | ￥8446 | 有现货 |
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| 100MG | ￥11399 | 有现货 |
|
| 500MG | 获取报价 | 有现货 |
|
| 1G | 获取报价 | 有现货 |
|
生物学信息
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产品名称Topoisomerase II inhibitor 14
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注意事项本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断
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产品简述Topoisomerase II inhibitor 14 (compound 2f) 是拓扑异构酶 II 的有效抑制剂，具有抗癌活性。Topoisomerase II inhibitor 14 诱导细胞凋亡，并将细胞周期阻滞在 S 期。Topoisomerase II inhibitor 14 具有抗氧化作用并降低 GSH、MDA 和 NO 的水平。
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产品描述Topoisomerase II inhibitor 14 (compound 2f) is a potent inhibtor of Topoisomerase II, with anticancer activity. Topoisomerase II inhibitor 14 induces apoptosis, and arrests cell cycle at S phase. Topoisomerase II inhibitor 14 exhibits antioxidant effect and decreases the level of GSH, MDA, and NO.
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体外实验——
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体内实验——
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同义词——
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通路Cell Cycle/DNA Damage
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靶点Topoisomerase
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受体Topoisomerase | Apoptosis | Antioxidant | NO Synthase
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研究领域——
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适应症——
化学信息
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CAS Number305343-00-4
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分子量332.19
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分子式C15H11Cl2N5
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纯度>98% (HPLC)
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溶解度——
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SMILESClC1=C(C2N3C=4C(NC3=NC(N)=N2)=CC=CC4)C=CC(Cl)=C1
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化学全称——
运输与储存
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储存条件(-20℃)
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运输条件With Ice Pack
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稳定性≥ 2 years
参考文献
1. Al-Karmalawy AA, et al. Novel fused imidazotriazines acting as promising top. II inhibitors and apoptotic inducers with greater selectivity against head and neck tumors: Design, synthesis, and biological assessments. Eur J Med Chem. 2023 Nov 5;259:115661.?
